Blockchain is a distributed ledger technology that is gaining significant attention from businesses and organizations of all sizes. Blockchain provides an immutable and transparent system for recording transactions and is highly resistant to tampering or corruption. However, implementing blockchain requires careful consideration of the underlying architecture and how it integrates with other systems and processes. In this article, we will provide a practical guide to blockchain architecture for businesses leveraging cloud architecture, domain-driven architecture, event-driven architecture, security, and trust.